Enviar este artículo por correo electrónico Células troncales mesenquimales de la papila apical y su papel prometedor en la biología radicular
Resumen
OBJETIVO: En la actualidad, la práctica odontológica ha centrado su atención en terapias regenerativas. Una nueva fuente de células troncales dentales ha sido hallada en la papila apical de dientes permanentes inmaduros humanos, sin embargo, no hay ningún estudio de revisión bibliográfica de esta nueva población celular y su papel prometedor en la biología radicular para posterior aplicación en endodoncia regenerativa. METODOLOGÍA: Se realizó una revisión en la literatura usando bases de datos como PubMed, MEDLINE, Science Direct, entre otras. Se utilizó el algoritmo de búsqueda: (Stem Cells OR Cell, Stem OR Cells, Stem OR Stem Cell OR Progenitor Cells OR Cell, Progenitor OR Cells, Progenitor OR Progenitor Cell OR Mother Cells OR Cell, Mother OR Cells, Mother OR Mother Cell OR Dental Papilla OR Papillae, Dental OR Dental Papillae OR Papilla, Dental) OR Papilla Apical AND Cell Proliferation OR Proliferation, Cell OR Cellular Proliferation OR Proliferation. No hubo restricción de lenguaje ni de sexo. Se buscaron estudios en humanos, y artículos de revisión en los últimos 5 años. RESULTADOS: La búsqueda arrojó 50 artículos de los cuales fueron seleccionados 30 basados en su abstract. CONCLUSIÓN: Es posible obtener y expandir células de la papila apical de dientes permanentes inmaduros con fenotipo de células troncales mesenquimales. Estas células pueden ser viables y son posibles candidatas estándar para ser usadas en terapias en regeneración de tejidos dentales.
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